Injections of polidocanol or a concentrated saline solution are injected into veins to cause them to collapse and form scar tissue that permanently closes them. Nearby veins take up re-routed blood flow. There is minimal discomfort from the injection and no post-treatment recovery time other than the recommendation that the patient wear support hose for a few days.

Sclerotherapy requires multiple treatments to close off all affected veins. Additional treatments may be needed from time to time as new enlarged veins appear. Side effects of sclerotherapy may include slight swelling, bruising, and redness and itching at injection sites.

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